Newly-crowned French champions Lyon paid the price for complacency when they threw away a 3-1 lead to minnows Guingamp who grabbed a late 3-3 draw in the opening match of the season.
Lyon pipped Lens to the line in May after beating their rivals on the final day at a packed Stade Gerland to end a half century of under-achievement.
But the south-eastern French side failed to get their campaign off to a winning start against gritty Brittany side Guingamp who only remained in the top flight by the skin of their teeth last season.
Lyon had looked to be coasting after profitting from early errors from the Bretons with Braziliana midfielder Juninho grabbing the first goal after just three minutes by tricking goalkeeper Ronan Le Crom with a deceptive shot from 20 metres.
Midfielder Stephane Carnot grabbed the equaliser for the home side on the 24th minute as the drizzle came down.
Both sides missed chances to break the deadlock with Lyon taking the initiative just before the break thanks to a header from unmarked defender Jean-Marc Chanelet following a pass from Juninho on 38.
Disorganisation in the host's defence put Lyon 3-1 ahead when Ivory Coast international defender Kouassi Koffi blundered gifting the ball to Sonny Anderson who gladly accepted it and struck into the net on 51.
Former Lyon striker Cedric Bardon missed his chance to reduce arrears, hitting straight to goalie Gregory Coupet, but made amends by recuperating the ball for a 3-2 scoreline just one minute from time.
Lyon paid the price for their complacency, lowering their guard as Guingamp made one last desperate push with Ivorian striker Didier Drogba succeeding four minutes into extra time netting between the legs of Coupet to the delight of the 14,000 fans at the Roudourou stadium.
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